Gimp around in 80 minutes
Because black is transparent in Screen mode (also Addition and Lighten Only) black pencil strokes drawn on a white layer will reveal the image underneath, just as if you had sketched all by hand. This is an easy way of creating convincing pencil/ink drawings from a scanned photo.
Manage without artistic plugins
There are several commercial plugins called things like charcoal, crayon or ink drawing that supposedly achieve these things. Certainly, these products can produce nice artistic outputs, but they never come close to the results you get using this method. Naturally, the quality of the final image depends a lot on the drawing in the screen layer, so this isn't an "instant artist" trick. A general advice is to reduce the number of shades in the background, otherwise too much of the underlaying image will show, and this will spoil the illusion. One way of improving coarse computer drawings is to use the Value Propagate filter and set it to more white. You can also create a crayon or charcoal look to an image by displacing or warping the pen strokes with a suitable displacement map, or just by using unusual brushes.
Instant cartoon pictures
A very simple way of creating drawings from scanned photos is of course to use one of the Edge-Detect filters. Running Sobel on a duplicate results in a transparent layer with a black outline of the image object. Having done this, it's easy to paint the underlaying layer in large clean areas, and you'll get something very similar to a picture in a comic book.
The Gimp User Manual
Last modified: 19 May 1998